At enrolment into the study cohort 66% were on antidiabetic treatment, among the patients included in this current study 71% started within one year prior to study start or after. We conducted this prevalence study using cross-sectional baseline data from DD2, a nationwide cohort study of newly diagnosed Type 2 DM patients enrolled from the practices of general practitioners (GPs) and hospital specialist outpatient clinics in Denmark since November 2010. As CRP is higher in females than males, we also wished to examine whether factors associated with elevated CRP in Type 2 DM differed between genders. We thus aimed to examine the prevalence of and modifiable factors associated with elevated CRP among newly diagnosed Type 2 DM patients included in the nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort study. Lower CRP levels have been reported among individuals with regular alcohol consumption and those under statin treatment. In cross-sectional studies of the general population, elevated levels of CRP are often found in older people, in those with high Body Mass Index, and in less physically active people. Information regarding elevated CRP levels and associated factors at the time of Type 2 DM diagnosis in a population-based setting is limited. Thus, for prevention purposes, early detection of elevated CRP levels and identification of modifiable factors associated with this condition are important. In patients with Type 2 diabetes mellitus (DM), the level of systemic inflammation, measured by C-reactive protein (CRP), may be a predictor of cardiovascular disease (CVD) and worse prognosis. Important modifiable risk factors for elevated CRP may vary by gender, and include low physical activity for men and central obesity and absence of statin use for women. ConclusionsĪmong newly diagnosed Type 2 DM patients, 40% had elevated CRP levels. The linear regression analysis conveyed an association between high CRP and increased fasting blood glucose. Sensitivity analyses showed consistent results with the full analysis. For both genders, elevated CRP was 1.4-fold increased in those with weight gain >30 kg since age 20 years. For men, CRP was primarily elevated among patients with no regular physical activity (aRR 1.5 (95% CI 1.1-1.9)), previous cardiovascular disease (aRR1.5 (95% CI 1.2-1.9) and other comorbidity. Among women, a lower risk of elevated CRP was observed in patients receiving statins (adjusted RR (aRR) 0.7 (95% confidence interval (CI) 0.6-0.9)), whereas a higher risk was seen in patients with central obesity (aRR 2.3 (95% CI 1.0-5.3)). More women (46%) than men (34%) had elevated CRP. In total, 405 out of the 1,037 Type 2 DM patients (40%) had elevated CRP levels (>3.0 mg/L). The median CRP value was 2.1 mg/L (interquartile range, 1.0 – 4.8 mg/L). We used linear regression to examine the association of CRP with other biomarkers. We assessed the prevalence of elevated CRP and calculated relative risks (RR) examining the association of CRP with lifestyle and clinical factors by Poisson regression, stratified by gender. MethodsĬRP was measured in 1,037 patients (57% male) with newly diagnosed Type 2 DM included in the prospective nationwide Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project. We aimed to examine the prevalence of and modifiable factors associated with elevated C-reactive Protein (CRP), a marker of inflammation, in men and women with newly diagnosed Type 2 Diabetes mellitus (DM) in a population-based setting.
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So make no mistake, the deduction isn't new but the addition of COVID-19-related costs is useful and offers more possible ways to reach that deduction. Many teachers know that they can claim a $250 tax break for many out-of-pocket costs. If a teacher had to cover the cost of plexiglass, well, that could be used toward that deduction, too. "The teachers deduction was expanded to include expenses for PPE and related COVID expenses," said Mark Luscombe, principal analyst for Wolters Kluwer Tax & Accounting.Īccording to the Internal Revenue Service, COVID-19 personal protective equipment includes face masks, disinfectant for use against COVID-19, hand soap, hand sanitizer, disposable gloves, as well as tape, paint or chalk to guide social distancing. Here are some tax breaks to consider: A break for teachersĮligible teachers now can deduct unreimbursed expenses for COVID-19 protective items to stop the spread of the virus in the classroom. Or if you saw a drastic reduction in your income - and had some extraordinary medical expenses - you might be able to deduct medical expenses for 2020 when you couldn't in the past. Those who had huge medical bills last year should gather up their paperwork to see if they possibly can deduct a portion of their high out-of-pocket expenses. Most taxpayers check the box to claim the standard tax deduction. This tax season, though, the pandemic has caused many people to want to know how they can deal with COVID-19-related medical costs. When you create a variety of potential outcomes, you will become less emotional, which will help you think more clearly.ĭoesn’t it always seem much easier to see and solve someone else’s problems than your own? You can recognize when your sister is getting all worked up over nothing, or that losing sleep over a meeting isn’t going to help. Then, think of some middle ground outcomes. Then, write down the best thing that could happen. When you find yourself worrying about a negative result, take a piece of paper and pen and write down the worst thing that can happen. When you find yourself stuck in a cycle of negative thinking, or are terrified of a negative outcome, positive thoughts often ring as untrue. Many people will tell you to just “think positive.” However, it isn’t always that easy. The list of positives will help to change your focus and keep you moving forward with less fear. If you are talking yourself out of something that you want, take the time to make a list of why you want it. When you catch yourself thinking negatively and talking yourself out of action, take a step back and remind yourself that the most successful people have also faced failure. When we think negative thoughts, like “It won’t work,” or “I can’t do that,” we are permitting ourselves to play it safe. 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Question: Something you shouldn't wear to a job interviewĪnswer: wife beater, a wife beater, wife beater tshirt, wifebeater, wife beater t shirt, a wife beater t shirt Question: A dangerous thing to do while drivingĪnswer: load a gun, loading a gun, load your gun, loading your gun Question: Something you shouldn't get your significant other for Valentine's Day Question: The best thing about living in an iglooĪnswer: beer always cold, cold beer, beer's always cold, keeps beer cold, keeps beer nice and cold, beer's always nice and cold, the beer's always cold, the beer stays cold, beer stays cold Question: Come up with a name for a beer made especially for monkeys Question: A not-very-scary name for a pirate Question: The name of a pizza place you should never order from Question: What's the first thing you would do if you could time travel?Īnswer: eat a dinosaur, eat some dinosaurs, eat dinosaurs Question: The name of the reindeer Santa didn't pick to pull his sleigh Question: Invent a family-friendly replacement word that you could say instead of an actual curse word Question: What would you do if you were left alone in the White House for an hour?Īnswer: pass a law, pass laws, pass some laws Question: Come up with the name of book that would sell a million copies, immediatelyĪnswer: The big book of boobs, big book of boobs Question: The best title for a new national anthem for the USA Question: The best thing about going to prisonĪnswer: free orange jumpsuit, free jumpsuit, orange jumpsuit, the free orange jumpsuit, the free jumpsuit, the orange jumpsuit Question: What would make baseball more entertaining to watch? 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Prepare to navigate a chilling ocean filled with strange creatures, explore alien ruins, and cooperate with your crewmates to complete missions on your voyage. Barotrauma is a 2D co-op survival horror submarine simulator, inspired by games like FTL: Faster Than Light, Rimworld, Dwarf Fortress and Space Station 13. Release date 13 March 2023 Official website Developer Fakefish Publisher Daedalic Entertainment Activation Steam Platforms PC PEGI - Tags Strategy Action Early Access Simulation Survival Horror. Barotrauma is a 2D co-op submarine simulator in space, with survival horror and RPG elements. Endworm - Official Barotrauma Wiki Endworm navigation search The Endworm is a titanic, worm-like creature, named after its ability to 'end' the lives of anybody who comes across it. Since it went into early access in 2019, they overhauled the campaign and tutorials, added new monsters, missions, and outposts, improved graphics and environments, implemented a scripted event system, and much much more. Following these key quests will help you progress through the game at a steady pace and. This game is a sci-fi submarine sim with both a single-player mode as well as co-op with up to 16 players who navigate the depths of Jupiter’s frozen moon Europa and fulfill various missions. MONSTERS MHGU (Switch) - How To Farm Unlimited Burned Husk. Plus, it has a wonderful community on board that has already pushed the game to the amazing milestone of more than 2.5 million players already calling this submarine spectacle their own! And there’s a classic joy in doing so.The time is nearly upon us when publisher Daedelic Entertainment and developers FakeFish and Undertow Games release the final version of their submarine survival simulation game Barotrauma! It is emerging to update 1.0 with lots of new features, such as a huge variety of u-boats and missions, disgusting enemies, varied biomes, and hilarious ragdoll physics. Content is available under CC BY-NC-SA 3.0 unless otherwise noted. Husk Crawler Tiger Thresher Mantis Coelanth Moloch Endworm More. Then act casual as water fills up the space, causing other players to panic. From Official Barotrauma Wiki < Template:AfflictionDisplayTest. But you can always hop into a game, run off to a secret area and bore a hole in the wall. Agony UNRATED, AGP::Epica, Agricola: All Creatures Big and Small. It’s also quite a menu bonanza that is low on design sensibility, and your mileage will depend on your friends or players you encounter. Glow Ball - The billiard puzzle game, Archery, KILLALLZOMBIES, monstercakes. It’s got some early access jank that prevents me from giving it a golden thumbs up without the caveats previously mentioned. But I’ll definitely be keeping an eye on it. My time was spent mostly flailing in panic as rooms filled with water.īut it’s too early to guarantee exactly what Barotrauma will become once the community gets their hands on it and it continues to cook. You can swim with your flashlight, repair things, craft new tools to use and eventually succumb to a tiny hole you didn’t realize was leaking until it filled half the sub. There isn’t really a single player story just yet, and multiplayer sees you just doing whatever hijinx you feel like at first, but you can get out of the sub and explore. I think that’s where FakeFish wants to take this game. Verdict: Because of its features and options, Notability is better suited for those who need more variety in their note-taking apps. Second, GoodNotes lets you create multiple notebooks, which is great for organizing your notes into different categories. First, the app supports landscape and portrait orientations, so you can take notes in whichever way is most comfortable. GoodNotes offers several features that make it an ideal choice for taking notes. Notability also offers an option called “Palm Rejection,” which means you don’t have to worry about your hand blocking the note-taking area while writing. Notability has two main modes for taking notes: handwriting and typing (typing is only available when using Notability’s keyboard). Notability allows you to take notes on your iPad using a stylus or finger. Both companies have spent years figuring out what is best for their users. Taking notesĪs far as taking notes goes, both GoodNotes and Notability have a lot to offer. Notability provides you with a tutorial that explains all of the gestures you can use with this app. Verdict: Undoubtedly, a note-taking app’s ease of use and accessibility are essential factors for many note-takers. GoodNotes also includes various tools for drawing and annotating your notes, which adds more detail to your notes. You can quickly create new notes, insert photos and videos, add text formatting, and more. The app’s user interface is intuitive, and all the features are easy to find and use. Once you have created a notebook, you can start taking notes by tapping on the “plus” button at the bottom of the screen. To create a new notebook, tap on the plus sign in the top-right corner. After opening the app, you are greeted with a list of all your notebooks. The GoodNotes app is also straightforward to use. Similarly, by tapping on any point of the note (whether it’s writing, typing, or a photograph), you may instantly go to that location in the audio file. The notes you took darken and fill in as the recording proceeds, allowing you to follow the notes as they appear while recording. The audio recording component is rather adaptable. Students may arrange their notes for easy retrieval after the lesson. On a single page of notes, pupils can write, draw, highlight, record audio, cut and paste content from the web, and even introduce material from the internet. This is an excellent feature because you don’t have to worry about keeping your notes manually! Notability also offers an option called “Auto-Save,” which means every time you take notes in Notability, it automatically saves them for later review. Notability has a simple user interface with only three buttons on the bottom toolbar: Create Note, Take Notes, and Record Audio/Video Lectures. This iPad note-taking app is straightforward to use. While both apps offer easy search and navigation, their approaches are very different. If you compare GoodNotes with Notability, the first thing to notice is the app’s layout and ease of use. Ability to create notebooks on any Apple device, including iPhone or iPad (with optional iCloud sync).The user interface is clean and straightforward, so it’s easy for beginners and more experienced users who want to take advantage of its advanced features. Supports various file types, including PDFs, photos, videos, and audio recordings.Ability to create and edit notebooks on any Apple device.GoodNotes has a lot of writing tools that set it apart from other note-taking apps. The user interface is clean and straightforward, so it’s easy for beginners and more experienced users who want to take advantage of its more advanced features. It supports various file types, including PDFs, photos, videos, and audio recordings. GoodNotes is an IOS app that lets you create and edit your digital notebook on any Apple device. Read your notes on other devices using Notability’s Mac, Windows, Android, and Chromebook apps.Record lectures and annotate PDFs simultaneously to capture lecture points.Sync documents with Google Drive or Dropbox for classroom collaboration.Add interactive elements like linkable URLs, text fields, and checkboxes for cross-platform compatibility.Type and write naturally with Apple Pencil and multi-touch: create notes, sign documents, annotate PDFs, draw diagrams or sketch images from your camera.Notability lets you take handwritten notes, type out text, and even record lectures all within the same note! Not only that, but Notability offers many great features to help make taking notes more accessible than ever, such as auto-saving (so you don’t have to worry about saving your notes), highlighting tools that allow you to color-code important information when taking notes, and more! Notable Features Notability is a note-taking app for your iPad. Campaigns of expansionĪ year after the original Age of Empires launched, Microsoft put out an expansion called The Rise of Rome. Still, history suggests that we’re about due for a bigger addition to the game - and if there’s one thing Age of Empires does well, it’s history. (Compare and contrast to new civilizations in Age of Empires III: Definitive Edition, which tend to cost about $5 apiece.) Even if you’re just in it for the single-player, there are two new civilizations to master, the Ottomans and the Malians - and Microsoft didn’t charge a penny for either one. The developers have expanded and refined AoE4 since launch, especially on the multiplayer side, where there’s almost always a new challenge to complete or rank to earn. Granted, it’s not as though there’s nothing left to do in the game. After eight exciting missions, I was done with the Rus campaign - and, essentially, done with the directed single-player component in Age of Empires IV. I learned a thing or two about the Rus, the Lithuanians and the Golden Horde, in addition to wooden building construction, the distinction between infantry swords and cavalry sabers, and how the Russian Orthodox Church helped shape the country’s history.Īnd, like the other campaigns in AoE4, it wasn’t especially long. Like the other campaigns in AoE4, the Rise of Moscow is an excellent journey, combining varied and challenging gameplay objectives with real-world documentary footage. PC gaming and RTS go together like the Delhi Sultanate and war elephants, so I dove in and started Dmitry Donskoy’s long and challenging war against the Golden Horde. I decided I’d get back around to it someday, and the opportunity arose when I came back from holiday break with a whole stack of mouse pads to review. That left only one campaign to complete: the Rus. Before I reviewed the game, I finished three of its historical campaigns: the English, the French and the Mongols. I fired it up to remind myself how to use it.įirst I had to wire the two devices together. Duet works really well and if you’re going to be working for a long time on a desk it’s a great solution. You could use one of those apps that allows you to use your iOS display as a secondary monitor, like the awesome Duet Display from to solve the same problem. What if you could just use a keystroke on your Mac to allow you to type on the iPad and then flip back to typing on the Mac? That would be pretty cool. But typing on the iPad is a pain without a real keyboard. Maybe do your web surfing on the Mac and read and write email on an iPad. One solution is to split tasks between your Mac and your iOS device. This is especially true if you’re on travel where it’s impractical to carry a second monitor around with you. If you have a MacBook or MacBook Pro, I bet there are times where you wish you had a little more screen real estate. Using a Bluetooth keyboard with the AppleTV can make you happier, and if you’re watching TV with a laptop right near you, why not use its keyboard instead of that aggravating remote? But most of the time we end up scrolling right/left/up/down and doing a lot of swearing when we try to type on the AppleTV. If you have voice recognition in your country for the Apple remote, that actually works surprisingly well, especially for passwords. The AppleTV is the most obvious problem – typing (even with the new remote) is a nightmare. Before I walk you through it, let’s set up a couple of problems it might solve. Typeeto from /… lets you use a Mac as a Bluetooth keyboard for your iOS devices, including the AppleTV. The normal price is a bit steep (regularly priced at $20), but absolutely worth it at the current limited time sale pricing, even for occasional use.I’ve got a cool little utility that may or may not solve a problem for you. If you spend most of your day near a Mac, Typeeto is a great investment that beats paying for separate mobile keyboard accessories for each device. If you prefer a different device name, Typeeto can customize that and more from the app preferences. I did find a potential Bluetooth software conflict in my testing, which seemed to disconnect the Knock app whenever Typeeto was activated, although other devices like my Magic Trackpad 2 continued to work without issue. Speaking of sound effects, I found that holding keys down too long while Typeeto is active caused the Mac to incorrectly trigger a repeated alert sound, although it didn’t interfere with anything on the device side. The Option-Command-V shortcut can be used to paste text copied on the Mac side directly to the device, while Command-V works for pasting current device clipboard contents. Other settings include white or black color themes, the option to remove the app icon from Dock, or turn off sound effects, which offer audible feedback when a connection is made. Typeeto automatically picks up the name of added devices, but these can be changed to whatever you’d like from the app preferences. While a device is active, a small window appears on the Mac display to confirming it’s in use, with animation as text is entered on the keyboard. With iOS and Android, it’s worth noting the initial connection should be initiated from the device itself for best results. Although the software can theoretically connect to an unlimited number of devices, Bluetooth itself is limited to eight connections at a time. Like other Bluetooth-connected devices, Typeeto works within a range of approximately 32 feet. 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OoT Randomizer rewrite, text speeds and main hacking. Windows 10 is recommended, but other OS that can install PowerShell could also be used. The tool depends on a computer with PowerShell support. You can download the software here if you want to customize your own ROM patch: That can easily be changed, thanks to an amazing software called Patcher64+ Tool, which allows you to toggle whatever feature you want on or off according to your liking, so you can create your own custom Ocarina of Time / Master Quest Redux ROM! Or you want the censored Gerudo textures, or you want a higher text speed (like 3x) or want certain features, and not others?
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